NOT KNOWN DETAILS ABOUT LDN-27219 PRECLINICAL RESEARCH

One significantly attention-grabbing compound is LDN-27219. Even though most tTG inhibitors are intended to bind towards the protein crosslinking Lively website, LDN-27219 rather binds into the nucleotide binding pocket with the enzyme whilst it is in its closed-state conformation, and stabilizes that conformation to circumvent crosslinking activit